Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF-κB Pathway

<div>The expressions of NF-κB p65 and 3-nitrotyrosine were detected in renal tissues at 12 hours in all groups (original magnification ×400). (a) In SO group, weak immunoreactivity of NF-κB was mainly shown in cytoplasts. (b) In SAP group, intense immunoreactivity of NF-κB was shown in nucleus. (c) In HRS group, lower immunoreactivity of NF-κB was shown in nucleus than SAP group. (d) In SO group, exceedingly weak immunoreactivity of 3-nitrotyrosine was shown in cytoplasts. (e) In SAP group, intense immunoreactivity of 3-nitrotyrosine was shown in cytoplasts. (f) In HRS group, lower immunoreactivity of 3-nitrotyrosine was shown in cytoplasts than SAP group.</div>

Mediators of Inflammation

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Figure 5

Figure 5: Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF-κB Pathway

Figure 5 | Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF-κB Pathway 