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Mediators of Inflammation
Volume 2015, Article ID 693260, 12 pages
Research Article

Genetic Deletion of Soluble Epoxide Hydrolase Attenuates Inflammation and Fibrosis in Experimental Obstructive Nephropathy

1Department of Physiology, National Yang-Ming University, Taipei 11221, Taiwan
2Institute of Anatomy and Cell Biology, National Yang-Ming University, Taipei 11221, Taiwan
3Division of Nephrology, Department of Medicine and Immunology Research Centre, Taipei Veterans General Hospital, Taipei 11221, Taiwan
4Division of Nephrology, Buddhist Tzu Chi General Hospital, Taipei Branch, Taipei 23142, Taiwan
5Department of Nursing, Chang Gung Institute of Technology, Taoyuan 33303, Taiwan

Received 29 September 2014; Revised 28 November 2014; Accepted 7 December 2014

Academic Editor: Tânia Silvia Fröde

Copyright © 2015 Chin-Wei Chiang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Hsin-Han Hou, Yi-Jen Liao, Sheng-Huang Hsiao, Song-Kun Shyue, and Tzong-Shyuan Lee, “Role of phosphatase activity of soluble epoxide hydrolase in regulating simvastatin-activated endothelial nitric oxide synthase,” Scientific Reports, vol. 5, pp. 13524, 2015. View at Publisher · View at Google Scholar
  • Yaoxian Liang, Ziyang Jing, Hui Deng, Zhengqian Li, Zhen Zhuang, Song Wang, and Yue Wang, “Soluble epoxide hydrolase inhibition ameliorates proteinuria-induced epithelial-mesenchymal transition by regulating the PI3K-Akt-GSK-3β signaling pathway,” Biochemical and Biophysical Research Communications, 2015. View at Publisher · View at Google Scholar
  • Jinlong He, Chunjiong Wang, Yi Zhu, and Ding Ai, “Soluble epoxide hydrolase: A potential target for metabolic diseases,” Journal of Diabetes, 2016. View at Publisher · View at Google Scholar
  • Chi-Hao Zhang, Lei Zheng, Liang Gui, Jia-Yun Lin, Yi-Ming Zhu, Wen-Sheng Deng, and Meng Luo, “Soluble epoxide hydrolase inhibition with t-TUCB alleviates liver fibrosis and portal pressure in carbon tetrachloride-induced cirrhosis in rats,” Clinics and Research in Hepatology and Gastroenterology, 2017. View at Publisher · View at Google Scholar
  • Qian Wang, Yan Liang, Yingjin Qiao, Xiangya Zhao, Yi Yang, Shengnan Yang, Bing Li, Qianru Zhao, Ling Dong, Songxia Quan, Rui Tian, and Zhangsuo Liu, “Expression of soluble epoxide hydrolase in renal tubular epithelial cells regulates macrophage infiltration and polarization in IgA nephropathy,” American Journal of Physiology-Renal Physiology, vol. 315, no. 4, pp. F915–F926, 2018. View at Publisher · View at Google Scholar
  • Jun-Yan Liu, “Inhibition of Soluble Epoxide Hydrolase for Renal Health,” Frontiers in Pharmacology, vol. 9, 2019. View at Publisher · View at Google Scholar