Genetic Deletion of Soluble Epoxide Hydrolase Attenuates Inflammation and Fibrosis in Experimental Obstructive Nephropathy

Figure 3

Genetic deletion of sEH attenuates the UUO-induced obstructive nephropathy. (a) Kidney specimens from WT and mice were stained with hematoxylin and eosin Y. Scale bar: 100 μm. (b) Quantification of histopathology of kidney: renal tubular dilation, renal tubular atrophy, leukocyte infiltration, and interstitial volume. Data are mean ± SEM from 8 mice. versus WT nonobstructed kidney; versus WT UUO kidney.

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