Relationship between Prolactin Plasma Levels and White Matter Volume in Women with Multiple Sclerosis

Table 1

Demographical and MRI data of patients according to the presence of Gd enhancement on MRI. All values are expressed as median (range) except for age and disease duration that are expressed as mean (SD).

	Patients with Gd enhancement on MRI	Patients without Gd enhancement on MRI
Age (years)	29 (6)	31 (6)	0.52
Disease duration (years)	2.9 (2.3)	3.6 (3.7)	0.22
Number of relapses in the previous 2 years	1.5 (0–6)	1 (0–3)	0.32
EDSS	1.5 (0–4.5)	1.5 (0–4.5)	0.47
PRL (ng/mL)	11.7 (6.2)	13.4 (8)	0.23
T2-LL (mm^3)	8516 (59930–1490)	3508 (48675–378)	<0.001
T1-LL (mm^3)	1458 (15399–45)	477 (15501–0)	0.006
WM volume (mm^3)	726,750; (659,865–823,248)	750,682; (685,150–820,434)	0.004
GM volume (mm^3)	810,380; (667344–897,404)	815,054; (694,489–929,6557)	0.231