Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells

Figure 6

Qualitative representation of the calprotectin modulatory effects on IL27-mediated protein and gene expression in HUVECs. Colour code: red: upregulation, bold red (arrow up): increased upregulation compared to IL27 stimulation only, dark red (arrow down): decreased upregulation compared to IL27 stimulation only, and green: downregulation. IL27 receptor: gp130/WSX-1 and calprotectin receptors: RAGE (advanced glucated end product receptor) and TLR4 (Toll-like receptor 4).