Expression Pattern of Fatty Acid Binding Proteins in Celiac Disease Enteropathy

Figure 3

LFABP expression in human small intestine. Indirect immunofluorescence analysis using anti-LFABP polyclonal antibodies (Alexa 488, green) and nuclei stained with DAPI (blue). Representative staining in duodenal sections of non-CD control ((a) and (b)) and CD patient at diagnosis (c) (magnification 20x). Confocal fluorescence microscopy using anti-LFABP polyclonal antibodies (Alexa 488, green) and nuclei stained with propidium iodide (red). Representative staining in duodenal sections of non-CD control ((d) and (e)) and CD patient at diagnosis (f) (magnification 63x + 1.7 zoom). Healthy tissue ((a), (b), (d), and (e)) shows LFABP expression in the villi enterocytes. Severe enteropathy ((c) and (f)) shows LFABP expression in the epithelium as well as the crypts closer to the epithelium.

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