Serum Uric Acid Increases Risk of Cancer Incidence and Mortality: A Systematic Review and Meta-Analysis

Table 1

Characteristics of all studies.

First author	Year	Study design	Origins	Sample size	Followup (years)	Baseline time	Sex	Cancer
Cancer incidence
Horsfall [4]	2014	Prospective cohort study	UK	205,484	5	2000–2012	Mixed	Lung
Strasak [10]	2009	Prospective cohort study	Austrian	78,850	12.4	1985–2003	Men	All
Kolonel [11]	1994	Prospective cohort study	Hawaii	7,889	27	1965–1968	Men	All
Hiatt [12]	1988	Prospective cohort study	USA	75,283	9.8	1965–1972	Men	All
Hiatt [12]	1988	Prospective cohort study	USA	88,547	9.8	1965–1972	Women	All
Cancer mortality
Taghizadeh [13]	2014	Prospective cohort study	Dutch	4,350	38	1965–1969	Men	All
Juraschek [14]	2014	Prospective cohort study	Scotland	15,083	22.7	1984–1987	Mixed	All
Kuo [8]	2013	Prospective cohort study	Taiwan	354,110	9	2000–2007	Mixed	All
Strasak [15]	2007	Prospective cohort study	Austrian	28,613	15.2	1985–2005	Women	All
Strasak [15]	2007	Prospective cohort study	Austrian	83,683	13.6	1985–2005	Men	All
Jee [16]	2004	Prospective cohort study	Korean	22,698	9	1992–1996	Men	All
Colangelo [3]	2002	Prospective cohort study	USA	20,433	26.2	1967–1973	Men	Colorectal cancer
Colangelo [3]	2002	Prospective cohort study	USA	15,149	26.2	1967–1973	Women	Colorectal cancer
Tomita [17]	2000	Prospective cohort study	Japanese	49,413	5.4	1975–1982	Men	All
Gapstur [18]	2000	Prospective cohort study	USA	20,475	25	1963–1973	Men	Pancreatic cancer
Gapstur [18]	2000	Prospective cohort study	USA	15,183	25	1963–1973	Women	Pancreatic cancer
Mazza [19]	1999	Prospective cohort study	Italy	3,282	12	Not reported	Mixed	All