Mediators of Inflammation

Research Article

Symmetric Dimethylarginine Is Not Associated with Cumulative Inflammatory Load or Classical Cardiovascular Risk Factors in Rheumatoid Arthritis: A 6-Year Follow-Up Study

Table 2

Univariable analysis of continuous factors.


	SDMA
	Coefficient (95% CI)	value

BMI	−0.5% (−1.1%, 0.0%)	0.063
HR	−0.1% (−0.3%, 0.1%)	0.380
SBP	0.0% (−0.1%, 0.2%)	0.653
DBP	0.1% (−0.2%, 0.3%)	0.633
Log₂ Reynolds Risk Score	1.5% (−0.8%, 3.9%)	0.191
Log₂ Framingham Risk Score	−0.1% (−3.2%, 3.2%)	0.955
eGFR	−0.3% (−0.5%, 0.0%)	0.024
Log₂ creatinine	12.0% (2.2%, 22.8%)	0.016
Log₂ AAUC CRP	0.2% (−3.4%, 3.9%)	0.916
Log₂ AAUC ESR	2.0% (−1.0%, 5.0%)	0.192

Results from univariable regression models, with log₂-transformed dependent variables. Coefficients were then antilogged, to represent the percentage change in the untransformed outcome for a unit increase in the factor. For log₂-transformed factors, the coefficient represents the increase in the outcome for a twofold increase in the untransformed factor. Significant at . BMI: body mass index (kg/M²), HR: heart rate, SBP: systolic blood pressure, DBP: diastolic blood pressure, eGFR: estimated glomerular filtration rate, CRP: C-reactive protein, and ESR: estimated sedimentation rate.