Research Article
Proteasome Inhibitor Bortezomib Suppresses Nuclear Factor-Kappa B Activation and Ameliorates Eye Inflammation in Experimental Autoimmune Uveitis
Table 1
Effect of high-dose versus low-dose bortezomib (Velcade) on EAUa.
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Data are compiled from three experiments in which similar results were obtained. bLow-dose bortezomib 0.15 mg/kg ip treatment. cHigh-dose bortezomib 0.75 mg/kg ip treatment. , via the Chi-square test, between saline and Vel (H) groups. #, via the Wilcoxon signed-rank test, between saline and Vel (H) groups. +, via the Wilcoxon signed-rank test, between Vel (L) and Vel (H) groups. |