Proteasome Inhibitor Bortezomib Suppresses Nuclear Factor-Kappa B Activation and Ameliorates Eye Inflammation in Experimental Autoimmune Uveitis

Table 2

Effect of etanercept versus bortezomib (Velcade) on EAU.

Treatment	Incidence	Mean peak disease score
Saline	8/9
Etanercept^a	3/6
Velcade^b	0/

Etanercept 5 mg/kg ip treatment.
^bBortezomib (Velcade) 0.75 mg/kg ip treatment.
, via the Chi-square test, between saline and bortezomib group.
^#, via the Wilcoxon signed-rank test, between saline and bortezomib group.