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Inclusion criteria | Age | 18–45 years | Sun exposure | UV index 5 | Nutrition, body mass index | Normal, 18.5–24.9 | Stage | Clark II, Clark III, Clark IV, and Clark V |
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Exclusion criteria | Age | >18 years; <45 years | Pregnancy | Yes | Condition present | Drug and/or alcoholic addiction | Treatment present | Systemic treatment with hormones, antidepressants, antioxidants, and immunomodulators | Other pathologies | Neurological, physiatrical, digestive, endocrinological, and cardiovascular diseases, liver-, renal-, and lung-related pathologies, metabolic disease, autoimmune, infections, inflammations, and other neoplastic diseases |
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Inclusion criteria | Age | 18–45 years | Sun exposure | UV index 5 | Nutrition, body mass index | Normal, 18.5–24.9 | Calcemia, calciuria, phosphatemia, alkaline phosphatase, parathormone, and C reactive protein. | Normal values |
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Exclusion criteria | Age | >18 years; <45 years | Pregnancy | Yes | Condition present | Drug and/or alcoholic addiction | Treatment present | Systemic treatment with hormones, antidepressants, antioxidants, and immunomodulators | Other pathologies | Neurological, physiatrical, digestive, endocrinological, and cardiovascular diseases, liver-, renal-, and lung-related pathologies, metabolic disease, autoimmune, infections, inflammations, and other neoplastic diseases |
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