The Effect of Cyclooxygenase Inhibition on Tendon-Bone Healing in an In Vitro Coculture Model

Figure 2

Stimulation of gene expression by recombinant BMP-2. Induction of target gene expression three days following the application of recombinant BMP-2 (500 ng) at the osteoblast region served as positive control. Gene expression was measured 3 days after the stimulation with BMP-2 (500 ng/mL) and normalized to housekeeping genes. Alpl: alkaline phosphatase; Bglap: bone gamma-carboxyglutamate protein; BMP-2: bone morphogenetic protein-2; Runx2: runt-related transcription factor 2. values are provided as follows: , , and .