IL-4 Inhibits IL-1β-Induced Depressive-Like Behavior and Central Neurotransmitter Alterations

Figure 2

(a) Effect of IL-4 injected 2 hours after injection of i.c.v. IL-1β on CORT concentration. Each value represents the mean ± SEM. compared to the CSF and compared to the IL-1β treated group. Control, ; IL-1β, ; IL-4 100 ng, ; IL-4 200 ng, . (b) Effect of IL-4 injection 2 hours after injection of i.c.v. IL-1β on PGE₂ concentration. Each value represents the mean ± SEM. The results of ELISA were analyzed by performing separate one-way ANOVA among the groups. Each value represents the mean ± SEM. compared to the CSF and compared to the IL-1β treated group. Control, ; IL-1β, ; IL-4 100 ng, ; IL-4 200 ng, .

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