Microcystins Induces Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Activation of NF-<svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2724495pt" id="M1" height="8.33029pt" version="1.1" viewBox="-0.0657574 -8.05784 9.46708 8.33029" width="9.46708pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g14-232" d="M520 405C520 434 497 457 469 457C411 457 359 401 300 331L203 216L238 377C241 391 243 406 243 417C243 443 234 457 212 457C175 457 104 420 22 347L39 310C70 333 95 348 105 348C108 348 109 336 105 313C84 205 64 113 34 -2L37 -12C77 -5 119 -1 161 2C175 73 188 138 193 154C200 162 217 180 228 187L275 67C300 3 329 -12 359 -12C390 -12 447 10 511 103L482 135C453 101 433 89 426 89C416 89 409 97 393 127C373 165 330 268 323 288C344 314 390 359 430 359C445 359 455 358 467 349C472 345 479 346 487 352C499 361 520 386 520 405Z"/></g></svg>B

<div>The MC-LR induced the expression of VCAM-1, ICAM-1, and TNF-<i>α</i> protein in HUVECs.</div>

Mediators of Inflammation

fig7

Figure 7

Figure 7: Microcystins Induces Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Activation of NF-<svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2724495pt" id="M1" height="8.33029pt" version="1.1" viewBox="-0.0657574 -8.05784 9.46708 8.33029" width="9.46708pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g14-232" d="M520 405C520 434 497 457 469 457C411 457 359 401 300 331L203 216L238 377C241 391 243 406 243 417C243 443 234 457 212 457C175 457 104 420 22 347L39 310C70 333 95 348 105 348C108 348 109 336 105 313C84 205 64 113 34 -2L37 -12C77 -5 119 -1 161 2C175 73 188 138 193 154C200 162 217 180 228 187L275 67C300 3 329 -12 359 -12C390 -12 447 10 511 103L482 135C453 101 433 89 426 89C416 89 409 97 393 127C373 165 330 268 323 288C344 314 390 359 430 359C445 359 455 358 467 349C472 345 479 346 487 352C499 361 520 386 520 405Z"/></g></svg>B 

Mediators of Inflammation

Microcystins Induces Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Activation of NF-B

Figure 7