| MMP | Role in IBD | Reference |
| MMP-1 | Prevention of fibrosis | [145] | MMP-2 | Generation of antiangiogenic factors, maintenance of epithelial barrier function, and prevention of fibrosis | [119, 135, 145] | MMP-3 | Generation of endostatin | [118] | MMP-7 | α-defensin activation, chemokine expression, wound healing, and generation of endostatin | [105, 106, 118] | MMP-8 | Neutrophil infiltration | [18] | MMP-9 | Chemokine expression, neutrophil infiltration, generation of anti-angiogenic factors, VEGF-A processing, decreased goblet cell differentiation, and prevention of fibrosis | [18, 107, 118, 119, 125, 134, 145] | MMP-10 | Wound healing, | [19] | MMP-13 | Activation of TNF-α and generation of endostatin | [111, 118] | MMP-20 | Generation of endostatin | [118] |
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