Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice

Figure 2

Irb alleviated diabetes-induced renal pathological changes. (a) Representative fields of the glomerulus stained with PAS (scale bars: 50 μm). (b) The mesangial expression score increased in db/db mice and decreased in db/db mice with Irb treatment. The bars in panel (b) show the mean expression in arbitrary units (error bars, S.D.). compared with db/m; compared with db/db, -test.

(a)

(b)