Research Article

A Single Bout of Fasting (24 h) Reduces Basal Cytokine Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of Normal Weight F344 Rats

Table 3

Correlational relationships between biomarkers of energy status and cytokine expression in WAT. Correlations between blood plasma concentrations and WAT cytokine concentrations for all rats (). Values are expressed as the Pearson correlation constant followed by the ( value).

Glucose (mg/dL)NEFA (mEq/L)Insulin (ng/mL)Leptin (pg/mL)Corticosterone (ug/dL)

Subcutaneous WAT
 TNF-α (pg/mg)0.28 (0.05)−0.18 (0.22)0.24 (0.09)0.40 (0.004)−0.21 (0.14)
 IL-1β (pg/mg)0.01 (0.95)−0.02 (0.90)−0.16 (0.26)0.37 (0.007)0.35 (0.01)
 IL-6 (pg/mg)−0.06 (0.70)−0.02 (0.90)−0.20 (0.17)0.26 (0.07)0.19 (0.18)
 IL-10 (pg/mg)0.40 (0.005)0.22 (0.12)0.24 (0.01)0.49 (0.0002)0.20 (0.18)
Intraperitoneal WAT
 TNF-α (pg/mg)0.25 (0.08)0.02 (0.87)0.35 (0.01)0.16 (0.28)0.25 (0.76)
 IL-1β (pg/mg)0.02 (0.90)0.04 (0.81)−0.12 (0.423)0.11 (0.46)0.46 (0.0007)
 IL-6 (pg/mg)−0.05 (0.71)0.01 (0.50)−0.17 (0.25)0.17 (0.24)0.36 (0.01)
 IL-10 (pg/mg)0.40 (0.004)−0.19 (0.18)0.35 (0.01)0.25 (0.09)0.30 (0.03)
Visceral WAT
 TNF-α (pg/mg)0.58 (<0.0001)−0.17 (0.23)0.54 (<0.0001)0.48 (0.00003)−0.09 (0.53)
 IL-1β (pg/mg)0.35 (0.14)−0.15 (0.31)0.33 (0.02)0.46 (0.0007)0.07 (0.66)
 IL-6 (pg/mg)−0.02 (0.87)0.02 (0.88)−0.08 (0.60)0.09 (0.53)0.20 (0.18)
 IL-10 (pg/mg)0.42 (0.002)−0.25 (0.08)0.43 (0.002)0.36 (0.01)0.10 (0.49)