Conjugated Bilirubin Differentially Regulates CD4+ T Effector Cells and T Regulatory Cell Function through Outside-In and Inside-Out Mechanisms: The Effects of HAV Cell Surface Receptor and Intracellular Signaling

Table 1

Demographic and clinical characteristics of HAV-infected pediatric patients and controls.

Characteristic	Healthy; controls; ()	Patients		value
		HAV+; CB: >0.3–2 mg/dL; ()	HAV+; CB: >2 mg/dL; ()
Gender (% female)	41	58	56	NS
Mean age (years ± SD)				NS
Mean ALT (IU/L ± SD)				NS
Mean AST (IU/L ± SD)				<0.05
Mean CB (mg/dL ± SD)				—
Anti-HAV IgM	−	+	+	—
Anti-HAV IgG	−	−	−	—

ALT: alanine aminotransferase; AST: aspartate aminotransferase; SD: standard deviation; NS: not significant.