Low-Dose Steroid Therapy Is Associated with Decreased IL-12 Production in PBMCs of Severe Septic Patients

Table 5

Generalized linear model analysis for the change in IL-1 response to identify independent factors among clinical characteristics and steroid use.

		Change in IL-1 response or (rho)	value
Age	−0.689	0.068	0.154
Sex			0.775
Male	−4.358	−8.6, −94.5–94.1
Female	0^†	−13.1, −23.5–153.5
APACHE II	3.110	0.292	0.006
Septic shock			0.083
Yes	−34.395	−10.8, −94.5–94.1
No	0^†	−3.8, −28.0–153.5
Low-dose steroid			0.472
Yes	−13.113	−10.3, −94.5–94.1
No	0^†	2.2, −28.0–153.5
Mortality			0.659
Yes	7.850	−8.5, −94.5–94.1
No	0^†	−9.9, −38.4–153.5

IL = interleukin; APACHE = Acute Physiology and Chronic Health Evaluation.
Data are presented as the median and range (in pg/mL) for categorical variables or the Spearman rank correlation coefficient (rho) value for continuous variables.
^†0 is set as a reference.