Mediators of Inflammation / 2016 / Article / Tab 6

Research Article

Low-Dose Steroid Therapy Is Associated with Decreased IL-12 Production in PBMCs of Severe Septic Patients

Table 6

Generalized linear model analysis for the change in IL-12 response to identify independent factors among clinical characteristics and steroid use.

Change in IL-12 response or (rho) value

Age−2.3690.0150.727
Sex0.036
 Male447.838253.725, −432.0–2059.9
 Female058.3, −813.8–1023.4
APACHE II−5.300−0.3160.095
Septic shock0.083
 Yes482.418176.4, −432.0–2059.9
 No0241.6, −813.8–1928.9
Low-dose steroid0.003
 Yes−750.74387.6, −432.0–679.7
 No0352.3, −813.8–2059.9
Mortality0.574
 Yes−140.57249.3, −432.0–679.7
 No0224.6, −813.8–2059.9

IL = interleukin; APACHE = Acute Physiology and Chronic Health Evaluation.
Data are presented as the median and range (in pg/mL) for categorical variables or the Spearman rank correlation coefficient (rho) value for continuous variables.
0 is set as a reference.

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