Low-Dose Steroid Therapy Is Associated with Decreased IL-12 Production in PBMCs of Severe Septic Patients

Table 7

Generalized linear model analysis for the change in TGF-1 response to identify independent factors among clinical characteristics and steroid use.

		Change in TGF-1 response or (rho)	value
Age	0.296	0.039	0.789
Sex			0.351
Male	−32.608	−13.4, −253.9–173.7
Female	0^†	0.0, −133.6–0.0
APACHE II	−5.110	−0.282	0.051
Septic shock			0.350
Yes	42.598	0.0, −253.9–173.7
No	0^†	0.0, −155.8–66.8
Low-dose steroid			0.388
Yes	−36.088	−13.4, −253.9–66.8
No	0^†	0.0, −155.8–173.7
Mortality			0.066
Yes	−75.079	−96.5, −253.8–13.4
No	0^†	0.0, −229.0–173.7

TGF = transforming growth factor; APACHE = Acute Physiology and Chronic Health Evaluation.
Data are presented as the median and range (in pg/mL) for categorical variables or the Spearman rank correlation coefficient (rho) value for continuous variables.
^†0 is set as a reference.