T Cell Response in Patients with Implanted Biological and Mechanical Prosthetic Heart Valves
Table 3
Profile of T cell subsets of peripheral blood from recipients with biological and mechanical heart valve prostheses and healthy volunteers.
T cells populations
Healthy donors,
Biological prosthesis,
Mechanical prosthesis,
CD3+%
78.27 (73.07; 82.52)
69.87 (65.68; 76.34)
69.96 (64.03; 71.72)
CD3+ abs.
1419.31 (1126.25; 1735.91)
1275.84 (1004.40; 1482.00)
1088.51 (977.34; 1185.92)
CD3+CD8+%
25.80 (20.64; 33.20)
24.28 (18.45; 27.32)
27.48 (24.58; 30.79)
CD3+CD8+ abs.
462.37 (349.70; 647.87)
412.00 (297.12; 597.77)
417.86 (351.00; 712.64)
CM Tcyt%.
11.50 (8.70; 16.38)
6.19 (3.93; 7.50)
6.75 (3.39; 14.85)
CM Tcyt abs.
51.69 (36.70; 74.30)
22.28 (18.98; 30.64)
24.63 (15.77; 69.37)
EM Tcyt%
31.82 (18.80; 43.55)
32.36 (19.75; 38.57)
24.14 (10.52; 33.38)
EM Tcyt abs.
122.56 (74.29; 196.04)
119.62 (74.36; 158.91)
94.26 (58.96; 139.48)
TEMRA Tcyt%
26.67 (19.58; 34.93)
49.41 (43.46; 58.83)
36.72 (35.04; 59.20)
TEMRA Tcyt abs.
104.32 (72.94; 188.42)
193.40 (129.60; 332.12)
220.78 (122.99; 270.64)
N Tcyt%
24.46 (16.51; 39.58)
13.08 (8.10; 15.63)
13.75 (5.59; 38.64)
N Tcyt abs.
98.47 (56.29; 199.74)
43.46 (28.49; 61.35)
83.67 (23.35; 135.62)
CD3+CD4+%
48.06 (41.04; 52.58)
40.74 (36.60; 48.37)
42.73 (41.01; 44.93)
CD3+CD4+ abs.
835.92 (624.17; 1096.10)
717.82 (580.50; 967.40)
697.17 (535.34; 755.99)
CM Th%
44.67 (38.42; 49.32)
39.60 (35.30; 46.42)
38.36 (30.46; 49.67)
CM Th abs.
338.29 (269.64; 484.11)
262.64 (227.73; 389.99)
276.91 (182.58; 368.45)
EM Th%
24.02 (17.54; 30.71)
26.01 (18.83; 29.66)
20.13 (12.71; 28.25)
EM Th abs.
197.64 (150.63; 229.90)
167.11 (135.15; 234.18)
152.18 (91.37; 201.64)
TEMRA Th%
0.82 (0.37; 1.67)
1.62 (0.94; 2.49)
1.54 (0.32; 6.47)
TEMRA Th abs.
6.17 (3.11; 13.58)
11.24 (6.24; 26.89)
16.45 (2.22; 36.04)
N Th%
29.88 (19.81; 36.00)
30.91 (24.50; 36.61)
25.87 (19.65; 48.46)
N Th abs.
222.99 (145.88; 369.81)
211.18 (140.38; 343.04)
219.42 (136.99; 337.60)
CD4/CD8
2.01 (1.34; 2.44)
1.93 (1.39; 2.17)
1.49 (1.38; 1.81)
Comments: denoted T cell subsets: N: naïve, CM: central memory, EM: effector memory, TEMRA: terminally differentiated CD45RA-positive effector cells, Tcyt: T cytotoxic (CD3+CD8+), and Th: T helper (CD3+CD4+). Difference between values compared to healthy volunteers, ; difference of parameter compared to healthy volunteers, ; difference between values compared to healthy volunteers, ; difference between values compared to healthy volunteers, .
