Research Article

T Cell Response in Patients with Implanted Biological and Mechanical Prosthetic Heart Valves

Table 6

Impact of hypertonic disease on T cells populations in biological prosthesis recipients.

T cells populationsHealthy donors, Hypertonic disease, No hypertonic disease, value

CD3+%78.27 (73.07; 82.52)71.47 (62.71; 84.21)69.26 (65.58; 74.10)1–3
CD3+ abs.1419.31 (1126.25; 1735.91)1515.78 (1003.36; 1643.88)1204.92 (1004.40; 1327.53)1–3
CD3+CD8+%25.80 (20.64; 33.20)24.95 (23.07; 38.91)22.28 (18.07; 27.32)n/s
CD3+CD8+ abs.462.37 (349.70; 647.87)474.05 (360.40; 715.17)374.22 (259.48; 485.60)n/s
CM Tcyt%.11.50 (8.70; 16.38)6.41 (3.92; 7.50)5.99 (3.93; 7.94)1–3
1-2
CM Tcyt abs.51.69 (36.70; 74.30)30.38 (18.98; 46.34)21.11 (13.17; 29.11)1–3
1-2
EM Tcyt%31.82 (18.80; 43.55)33.21 (26.71; 42.60)27.09 (15.97; 35.61)n/s
EM Tcyt abs.122.56 (74.29; 196.04)162.12 (134.98; 201.94)115.56 (55.09; 130.77)2-3
TEMRA Tcyt%26.67 (19.58; 34.93)49.41 (43.46; 58.83)49.07 (40.68; 60.38)1–3
1-2
TEMRA Tcyt abs.104.32 (72.94; 188.42)206.02 (140.19; 443.37)173.57 (112.81; 284.02)1–3
1-2
N Tcyt%24.46 (16.51; 39.58)7.53 (3.45; 12.06)14.00 (10.98; 15.85)1–3
1-2
2-3
N Tcyt abs.98.47 (56.29; 199.74)33.37 (13.72; 43.46)46.67 (39.46; 64.74)1–3
1-2
CD3+CD4+%48.06 (41.04; 52.58)40.74 (32.23; 54.46)41.81 (36.60; 48.37)n/s
CD3+CD4+ abs.835.92 (624.17; 1096.10)817.20 (529.20; 1089.20)705.31 (580.50; 948.64)n/s
CM Th%44.67 (38.42; 49.32)46.91 (36.38; 48.95)38.68 (35.23; 44.05)1–3
CM Th abs.338.29 (269.64; 484.11)297.29 (221.39; 468.69)251.99 (227.73; 340.65)1–3
EM Th%24.02 (17.54; 30.71)33.21 (21.28; 36.49)24.28 (17.82; 28.74)n/s
EM Th abs.197.64 (150.63; 229.90)237.85 (155.53; 284.65)162.54 (121.90; 187.07)1–3
2-3
TEMRA Th%0.82 (0.37; 1.67)2.26 (0.94; 3.17)1.62 (0.90; 2.49)1–3
TEMRA Th abs.6.17 (3.11; 13.58)18.46 (4.25; 33.43)11.23 (6.24; 26.89)1–3
N Th%29.88 (19.81; 36.00)22.24 (16.52; 27.73)35.46 (27.88; 39.09)2-3
N Th abs.222.99 (145.88; 369.81)159.70 (87.42; 317.64)226.13 (140.38; 382.83)n/s
CD4/CD82.01 (1.34; 2.44)1.52 (1.16; 2.41)2.01 (1.47; 2.17)n/s

n/s: not significant.