Soluble Urokinase-Type Plasminogen Activator Receptor Plasma Concentration May Predict Susceptibility to High Altitude Pulmonary Edema

Table 2

Inflammatory markers and physiologic parameters of HAPE-susceptible and non-HAPE-susceptible persons at sea level (normoxia) and during acute hypoxic exposure.

	Normoxia			Hypoxia
	Non-HAPE-s	HAPE-s		Non-HAPE-s	HAPE-s
Heart rate (1/min)				0.07				0.13
SaO2 (%)			0.01			0.74
PaO2 (kPa)			0.81			1.00
LLS-AMS			0.64			0.97
suPAR (ng/ml)			0.04			0.66
CRP (mg/L)			0.93			0.25
IL-6 (ng/L)			0.53			0.62

Values are given as mean ± SD. SaO₂: oxygen saturated hemoglobin fraction and LLS-AMS: Lake Louise score for acute mountain sickness; the cutoff value for the presence of AMS is defined as LLS-AMS ≥ 5 [29, 30].