Inhibition of Macrophage Migration Inhibitory Factor Protects against Inflammation and Matrix Deposition in Kidney Tissues after Injury

<div>Enhanced MIF expression in TECs after AA injury. (a) ELISA assay revealed AA increased MIF levels in NRK-52E cells in a concentration-dependent manner. (b) qRT-PCR assay showed that MIF mRNA expression was increased in AA-treated NRK-52E cells. (c) Immunofluorescence staining revealed enhanced expression of MIF, M-CSF, and MCP-1 in AA-treated NRK-52E cells. Bar: 50 <i>μ</i>m.</div>

Mediators of Inflammation

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Figure 5

Figure 5: Inhibition of Macrophage Migration Inhibitory Factor Protects against Inflammation and Matrix Deposition in Kidney Tissues after Injury 