Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway

Figure 1

Effects of 2% DMSO and shikonin on the liver function and pathology of healthy mice. (a) The levels of serum ALT and AST in the four groups did not differ. Data are given as means ± SD (, ). The serum levels of TNF-α, IL-1β, and IFN-γ of four groups were evaluated in each group with ELISAs (, ). (b) Representative hematoxylin-and-eosin-stained sections of the liver. Original magnification, ×200.

(a)

(b)