The Initial Months of Antiretroviral Therapy and Its Influence on AGEs, HMGB1, and sRAGE Levels in Asymptomatic HIV-Infected Individuals

Table 1

Clinical data of 30 PLWHA before and after cART initiation.

Variable	M0 (MEAN ± SD)	M1 (MEAN ± SD)	value
CD4+ T count (cells/mm^3)			<0.0001
HIV VL (RNA copies/mm^3)			0.019
Undetectable HIV VL	—	80.0%	—
cART regimen – NRTI + NNRTI	—	83.3%	—
cART regimen – NRTI + PI/r	—	16.7%	—

PLWHA: people living with HIV/AIDS; cART: combined antiretroviral therapy; VL: viral load; NRTI: nucleoside reverse transcriptase inhibitor; NNRTI: nonnucleoside reverse transcriptase inhibitor; PI/r: protease inhibitors reinforced with ritonavir; M0: before cART initiation; M1: after cART initiation. Statistical tests: gamma distribution for CD4+ T cell count and Poisson to HIV VL.