Interleukin-17A Gene Variability in Patients with Type 1 Diabetes Mellitus and Chronic Periodontitis: Its Correlation with IL-17 Levels and the Occurrence of Periodontopathic Bacteria
Table 4
IL-17A −197A/G (rs2275913) genotype and allele frequencies in healthy controls and patients with CP stratified by smoking status.
IL-17A −197
Control nonsmokers
Control smokers
CP nonsmokers
CP smokers
Genotype and allele
(%)
(%)
(%)
(%)
AA
10 (9.2)
8 (18.2)
28 (16.2)
4 (6.6)
AG
49 (45.4)
22 (50.0)
67 (38.7)
24 (39.3)
GG
49 (45.4)
14 (31.8)
0.16
78 (45.1)
33 (54.1)
0.15
0.22
0.04
AA + AG versus GG
59 versus 49 (54.6/45.4)
30 versus 14 (68.2/31.8)
0.09
95 versus 78 (54.9/45.1)
28 versus 33 (45.9/54.1)
0.14
0.10
0.02
A
69 (31.9)
38 (43.2)
123 (35.5)
32 (26.2)
G
147 (68.1)
50 (56.8)
0.04
223 (64.5)
90 (73.8)
0.04
0.22
0.01
CP = chronic periodontitis, = number of subjects, and value < 0.05. comparison of groups of nonsmokers. comparison of groups of smokers.
