Research Article

Interleukin-17A Gene Variability in Patients with Type 1 Diabetes Mellitus and Chronic Periodontitis: Its Correlation with IL-17 Levels and the Occurrence of Periodontopathic Bacteria

Table 6

Levels of IL-17 in correlation with IL-17A −197A/G (rs2275913) genotypes in patients with CP#.

IL-17A −197IL-17 unstimulated (pg/mL); median (25–75 quartiles)

Genotype

AA + AG190.98 (0.25–8.53)
GG110.27 (0.00–0.54)0.04

IL-17A −197IL-17 stimulated by P.g. (pg/mL); median (25–75 quartiles)

Genotype

AA + AG191.51 (0.50–4.56)
GG110.10 (0.00–1.51)0.02

CP = chronic periodontitis, = number of subjects, value < 0.05 (Kruskal-Wallis test, ANOVA), and P.g. = Porphyromonas gingivalis.
Levels of IL-17 were available in 30 patients with CP.
#Only significant differences were shown.