Regulatory T Cell Induced by Poria cocos Bark Exert Therapeutic Effects in Murine Models of Atopic Dermatitis and Food Allergy

Figure 4

Effect of PCB extract on ovalbumin-induced diarrhea, anaphylactic response, and rectal temperature. OVA-induced food allergic symptoms were evaluated and scored by criteria for diarrhea and the anaphylactic response for 1 h after challenge with OVA. The diarrhea score (a), diarrhea occurrence (%, score ≥2) (c), anaphylactic response score (b), and anaphylactic response occurrence (%, score ≥2) (d) were evaluated on all challenges. (e) Rectal temperature was measured every 15 min for 1 h after the sixth OVA challenge. (f) Body weight during experiments. Data are presented as mean ± SD. Bars represent significant differences from the sham group at and versus sham. Data were analyzed using one-way repeated measures of ANOVA followed by Dunnett’s post hoc test.

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