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Mediators of Inflammation
Volume 2016, Article ID 3481371, 13 pages
Review Article

Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?

1Manchester Collaborative Centre for Inflammation Research, University of Manchester, 46 Grafton Street, Manchester M13 9NT, UK
2Department of Microbiology and Cell Science, College of Agricultural and Life Sciences, University of Florida, 1355 Museum Drive, Gainesville, FL 32611-0700, USA

Received 24 March 2016; Revised 1 June 2016; Accepted 4 July 2016

Academic Editor: Luca Cantarini

Copyright © 2016 Gloria Lopez-Castejon and Mariola J. Edelmann. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [11 citations]

The following is the list of published articles that have cited the current article.

  • Guan-Zhong Qiu, Wei Sun, Ming-Zhu Jin, Jing Lin, Pei-Gang Lu, and Wei-Lin Jin, “The bad seed gardener: Deubiquitinases in the cancer stem-cell signaling network and therapeutic resistance,” Pharmacology & Therapeutics, 2016. View at Publisher · View at Google Scholar
  • Christian Setz, Melanie Friedrich, Pia Rauch, Kirsten Fraedrich, Alina Matthaei, Maximilian Traxdorf, and Ulrich Schubert, “Inhibitors of Deubiquitinating Enzymes Block HIV-1 Replication and Augment the Presentation of Gag-Derived MHC-I Epitopes,” Viruses, vol. 9, no. 8, pp. 222, 2017. View at Publisher · View at Google Scholar
  • Ben A. Bailey-Elkin, Robert C.M. Knaap, Marjolein Kikkert, and Brian L. Mark, “Structure and function of viral deubiquitinating enzymes,” Journal of Molecular Biology, 2017. View at Publisher · View at Google Scholar
  • Tycho E.T. Mevissen, and David Komander, “Mechanisms of Deubiquitinase Specificity and Regulation,” Annual Review of Biochemistry, vol. 86, no. 1, pp. 159–192, 2017. View at Publisher · View at Google Scholar
  • Ashish Kabra, Catherine A. Benson, and Ying Li, “Backbone 1H, 13C, and 15N resonance assignments of deubiquitinase A in non-phosphorylated and phosphorylated forms,” Biomolecular NMR Assignments, 2018. View at Publisher · View at Google Scholar
  • Xingqin Wang, Julei Zhang, Hao Guan, Dahai Hu, Zhenzhen Li, Yanhui Jia, Shichao Han, Fu Han, and Wei Zhang, “Klf4 alleviates lipopolysaccharide-induced inflammation by inducing expression of MCP-1 induced protein 1 to deubiquitinate TRAF6,” Cellular Physiology and Biochemistry, vol. 47, no. 6, pp. 2278–2290, 2018. View at Publisher · View at Google Scholar
  • Sirsendu Jana, Michael Brad Strader, Fantao Meng, Wayne Hicks, Tigist Kassa, Ivan Tarandovskiy, Silvia De Paoli, Jan Simak, Michael R. Heaven, John D. Belcher, Gregory M. Vercellotti, and Abdu I. Alayash, “Hemoglobin oxidation–dependent reactions promote interactions with band 3 and oxidative changes in sickle cell–derived microparticles,” JCI Insight, vol. 3, no. 21, 2018. View at Publisher · View at Google Scholar
  • Hongrui Li, Zizhao Zhao, Jing Ling, Linhui Pan, Xibao Zhao, Huihui Zhu, Juan Yu, Bin Xie, Jianzhong Shen, and Weilin Chen, “USP14 promotes K63-linked RIG-I deubiquitination and suppresses antiviral immune responses,” European Journal of Immunology, 2018. View at Publisher · View at Google Scholar
  • Pablo Palazón-Riquelme, Jonathan D Worboys, Jack Green, Fatima Martín-Sánchez, Gloria López-Castejón, Ana Valera, Carolina Pellegrini, and David Brough, “USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation,” EMBO Reports, vol. 19, no. 10, 2018. View at Publisher · View at Google Scholar
  • Jinfang Zhang, Fabin Dang, Junming Ren, and Wenyi Wei, “Biochemical Aspects of PD-L1 Regulation in Cancer Immunotherapy,” Trends in Biochemical Sciences, 2018. View at Publisher · View at Google Scholar
  • Chunhui Yuan, Zi-Lu Qu, Xiao-Lei Tang, Qi Liu, Wei Luo, Chun Huang, Qin Pan, and Xiao-Lian Zhang, “Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan Induces IL-10-Producing B Cells and Hinders CD4+Th1 Immunity,” iScience, vol. 11, pp. 13–30, 2019. View at Publisher · View at Google Scholar