Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice

<div>Matrine inhibits neutrophil infiltration. Hematoxylin and eosin staining was used for histological examination of airway inflammation in lung tissue (magnification, 400x). N group: normal control mice; LPS group: LPS treatment only; M10 group: 10 mg/kg matrine plus LPS; M20 group: 20 mg/kg matrine plus LPS.</div>

Mediators of Inflammation

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Figure 5

Figure 5: Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice 