Research Article

CCR9 Is a Key Regulator of Early Phases of Allergic Airway Inflammation

Figure 6

CCR9 expression in eosinophils regulates their recruitment to inflamed lung. 2, 6, 24, and 48 h after the last OVA boost, BALF from OVA-sensitized/challenged mice was collected and analyzed by FACS. (a) Siglec-F+ SS cells were plotted. (b) Quantitation of eosinophils in WT and KO mice during inflammation. (c) Percentage and CCR9-expressing eosinophils in WT mice. Data are representative of 2 independent experiments and represent mean ± SD. –5 for each group (,  , and when compared with WT mice or when compared each time with control group).
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