CCR9 Is a Key Regulator of Early Phases of Allergic Airway Inflammation

Figure 7

Lymphocyte recruitment during airway inflammation is affected in absence of CCR9. 2, 6, 24, and 48 h after the last OVA-challenge, BALF from sensitized mice was collected and FACS analysis of (a) CD4 and (d) CD8 T-lymphocytes is shown. Percentage of CD4+ (b) and total number (e) of CD4+ T-lymphocytes gated in region of lymphocytes. CCR9+ cells were analyzed in (c) CD4+ or (f) CD8+ T-lymphocytes. Data are representative of 2 independent experiments and represent mean ± SD. –5 for each group (,  , and when compared with WT mice or when compared each time with control group).

(a)

(b)

(c)

(d)

(e)

(f)