Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis

Figure 6

Translocation of PBMC NF-B p65 subunit was inhibited by Mar1 in CLP mice. (a) NF-B p65 in cytoplasm decreased after CLP surgery but increased by Mar1. (b) NF-B p65 increased in CLP mice, but Mar1 decreased level of NF-B p65 in nucleus. NF-B p65 band from the experiments was normalized by -actin or lamin B1. . Data are expressed as means ± SEM. versus the CLP group.

(a)

(b)