Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces

Figure 2

Metabolism and balance of intestinal sphingolipids in physiological conditions and IBD. (a) Interconnected pathways of intestinal sphingolipid metabolism. (b) In the healthy state, intestinal sphingolipids are in a “functional equilibrium” (left); in the inflamed state of IBD, an unbalance of this equilibrium occurs, favoring the inflammatory disease (right).

(a)

(b)