Fostering Inflammatory Bowel Disease: Sphingolipid Strategies to Join Forces

Figure 3

Inflammatory roles of sphingolipids in IBD. (a) Simple sphingolipids (C1P, Cer, and S1P) act as potent proinflammatory messengers, favoring and exacerbating the IBD condition. (b) Complex sphingolipids (SM and GSLs) exert several anti-inflammatory effects.

(a)

(b)