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Mediators of Inflammation
Volume 2016, Article ID 3958453, 9 pages
http://dx.doi.org/10.1155/2016/3958453
Research Article

miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFα to Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose

1Department of Anatomy and Cell Biology, Wayne State University, Detroit, MI 48201, USA
2Department of Ophthalmology, Wayne State University, Detroit, MI 48201, USA

Received 10 December 2015; Revised 29 January 2016; Accepted 31 January 2016

Academic Editor: Ulrich Eisel

Copyright © 2016 Eun-Ah Ye and Jena J. Steinle. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [21 citations]

The following is the list of published articles that have cited the current article.

  • Eun-Ah Ye, Li Liu, Youde Jiang, Jenny Jan, Subhash Gaddipati, Susmit Suvas, and Jena J. Steinle, “miR-15a/16 reduces retinal leukostasis through decreased pro-inflammatory signaling,” Journal of Neuroinflammation, vol. 13, no. 1, 2016. View at Publisher · View at Google Scholar
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  • Eun-Ah Ye, and Jena J. Steinle, “miR-146a suppresses STAT3/VEGF pathways and reduces apoptosis through IL-6 signaling in primary human retinal microvascular endothelial cells in high glucose conditions,” Vision Research, 2017. View at Publisher · View at Google Scholar
  • Shali Chen, Biao Feng, Anu Alice Thomas, and Subrata Chakrabarti, “miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes,” Plos One, vol. 12, no. 3, pp. e0173918, 2017. View at Publisher · View at Google Scholar
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  • Eun-Ah Ye, and JenaJ Steinle, “Regulatory role of microRNA on inflammatory responses of diabetic retinopathy,” Neural Regeneration Research, vol. 12, no. 4, pp. 580, 2017. View at Publisher · View at Google Scholar
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