miR-146a Attenuates Inflammatory Pathways Mediated by TLR4/NF-κB and TNFα to Protect Primary Human Retinal Microvascular Endothelial Cells Grown in High Glucose

Figure 3

Protein levels of TLR4, MyD88, IRAK1, and TRAF6 levels in REC. REC were cultured in normal glucose (5 mM, NG) or high glucose (25 mM, HG). REC transfected with miR-146a mimic had reduced levels of TLR4, MyD88, IRAK1, and TRAF6, compared to that of control HG group. A representative blot is shown. versus NG, versus HG, and versus miR-146a. A minimum of was used for all data. Data are mean ± SEM.

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