The Role of the IL-20 Subfamily in Glaucoma

Figure 3

STAT3 activation in normal human dermal fibroblasts (white bars, ) and patient fibroblasts with the IL-20RB T104M mutation (dark bars, ) with and without cytokine stimulation: between cytokine treated and untreated cells; and comparing fibroblasts with the T104M IL-20RB mutation versus wild-type cells with the same cytokine treatment (reprinted with copyright permission from Journal of Ocular Pharmacology and Therapeutics). IL-20 was added at 100 or 200 ng/mL and IL-19 and IL-24 were used at 100 ng/mL.