Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury

Figure 4

TUDCA ameliorated Aldo-induced ER stress. (a) Relative mRNA expression of GRP78 compared to expression of GAPDH. (b) mRNA expression of GRP94 relative to the expression of GAPDH. (c) Representative Western blots of CHOP and caspase-12. (d) Relative expression of CHOP to expression of β-actin. (e) Relative expression of caspase-12 to expression of β-actin. Values are mean ± SEM (). , Sham+V group versus Aldo+V group, , Aldo+V group versus Aldo+TUDCA group.

(a)

(b)

(c)

(d)

(e)