Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury

Figure 6

TUDCA attenuated Nlrp3 inflammasome activation in Aldo-infused mice. (a) Representative Western blots of Nlrp3 and ASC. (b) Relative expression of Nlrp3 to the expression of β-actin. (c) Relative expression of ASC to the expression of β-actin. (d) Representative Western blots of IL-1β and IL-18. (e) Relative expression of IL-1β to expression of β-actin. (f) Relative expression of IL-18 to the expression of β-actin. Values are mean ± SEM (). , Sham+V group versus Aldo+V group, , Aldo+V group versus Aldo+TUDCA group.

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