Clinical Study

Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia

Table 1

Patient demographics and diagnosis and details of lipoprotein apheresis treatment.

Patient
()
Age, years Male ()
Female ()
Treatment frequencyProcessed volume, mLDALI configurationDiagnosisCAD

147MaleWeekly10000 1250HyperLp(a)AWA
262MaleWeekly10000 1250HyperLp(a) Yes
352MaleBiweekly10000 1250HyperLp(a) Yes
443MaleBiweekly10000 1250HyperLp(a) Yes
549MaleBiweekly10000 1000HyperLp(a) Yes
652FemaleBiweekly10000 1250HyperLp(a) Yes
750MaleWeekly100001250HyperLp(a) Yes
873MaleBiweekly100001000HyperLp(a)Yes
951MaleWeekly100001250HyperLp(a)Yes
1063MaleWeekly100001250HyperLp(a)Yes
1166MaleWeekly100001250HyperLp(a)Yes

DALI, Direct Adsorption of Lipids; HyperLp(a), hyperLp(a)lipoproteinemia; CAD, coronary artery disease; AWA, arterial wall atherosclerosis assessed by angiography but no CAD.