Cannabinoid CB2 Receptor Mediates Nicotine-Induced Anti-Inflammation in N9 Microglial Cells Exposed to β Amyloid via Protein Kinase C

Figure 1

Nicotine decreased TNF-α and IL-6 releases from Aβ-stimulated microglial cells in a dose-dependent manner. (a) Aβ exposure increased iNOS expression. The N9 microglial cells were exposed to different concentrations of Aβ for 24 h (). (b) Nicotine decreased TNF-α release (). (c) Nicotine decreased IL-6 release (). Results are expressed as means ± SD, , , ; n.s.: no significance.

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