Elevated Plasma Level of Interferon-λ1 in Chronic Spontaneous Urticaria: Upregulated Expression in CD8⁺ and Epithelial Cells and Induction of Inflammatory Cell Accumulation

Table 3

The number of IFN-λ1 expressing cells (double positive cells)/mm² and the percentage of IFN-λ1 expressing cells in each cell type examined. Data shown are the median (range) value from 6 different donors. Positively stained cells in each section were counted for more than 30 fields (magnification 400).

Cell type	Number of double positive cells/mm^2	% of double positive cells in each cell type
Try^+MC	3.8 (2.1–10.6)	81.1 (61.5–96.2)
Chy^+MC	58.7 (27.0–120.4)	93.9 (93.7–97.5)
Eosinophils	3.5 (1.9–7.6)	26.2 (17.8–52.6)
Macrophages	0.6 (0.4–1.9)	52.8 (34.8–87.7)
CD8^+T cells	0.0 (0.0–0.0)	0.0 (0.0–0.0)
B cells	1.6 (1.1–6.6)	92.9 (62.1–93.2)
Neutrophils	0.8 (0.3–1.2)	20.1 (15.2–30.6)