|
| Markers used to identify subset | Reference | Frequency | Phenotype | Function |
|
| BDCA2+ CD123+ | Tucci et al. [82] | ↓ in blood, correlated with LN and
↑ in kidney (more than other DC subsets) | | |
|
BDCA2+ (blood) and
BDCA4+ (kidney) | Fiore et al. [78] | ↓ in blood in active disease and
↑ in kidney (more than other DC subsets) | DCs in kidney were immature (DC-LAMP−), localized to tubulointerstitium, in clusters, and lacked dendrites | |
|
| BDCA2+ Lin.− HLA-DR+ | Migita et al. [77] | ↓ in blood | | |
|
| CD11c− CD16− HLA-DR+ | Henriques et al. [80] | ↓ in blood in active disease | | |
|
| BDCA2+ | Kwok et al. [90] | Normal in blood | ↓ IFNα production by PBMC per pDC upon CpG stimulation | |
|
| BDCA2+ BDCA4+ CD123+ | Jin et al. [79] | ↑ in blood per total PBMC | Normal HLA-DR, CD86, CD83, CCR7 | ↑ T cell proliferation in MLR |
|
| BDCA2+ CD11c− | Gerl et al. [81] | na | Normal HLA-DR, CD86, CD83, CCR7, CD40, BAFF, CCR1, and CCR5 and ↓ CMKLR1 | ↑ basal and CCL19-specific migration |
|
| BDCA-2+ CD4+ CD11c− Lin− | Hagberg and Rönnblom [86] | | ↓ SLAMF5/CD84, SLAMF7/CRACC/CD319, normal SLAMF1, SLAMF2/CD48, SLAMF3/CD229, SLAMF4/CD244, and SLAMF6/CD352 | |
|
