Radiotherapy Suppresses Bone Cancer Pain through Inhibiting Activation of cAMP Signaling in Rat Dorsal Root Ganglion and Spinal Cord

Figure 4

Alterations of cAMP concentration and PKA activity in DRG and the spinal cord after TCI with or without radiotherapy. (a and b) cAMP concentration. (c and d) PKA activity. The tissues were collected on postoperative days 10 and 14, that is, 1 and 5 days after radiotherapy, respectively. Each group included four samples with two ganglia in each sample. versus sham; versus TCI + sham.

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