Peroxisome Proliferator-Activated Receptor α Reduces Endothelin-1-Caused Cardiomyocyte Hypertrophy by Inhibiting Nuclear Factor-κB and Adiponectin

<div>Effects of ET-1 on the association of adiponectin, NF-κB, and PPARα in nuclei of cultured human cardiomyocytes. Nuclear proteins extracted from cells were immunoprecipitated with antibodies against adiponectin (ADN) or control mouse IgG and then separated by 12% SDS-PAGE gels before immunoblotting with antibodies against p65 (a), PPARα (b), and adiponectin (ADN) (c). The results were obtained from three independent experiments.</div>

Mediators of Inflammation

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Figure 5

Figure 5: Peroxisome Proliferator-Activated Receptor α Reduces Endothelin-1-Caused Cardiomyocyte Hypertrophy by Inhibiting Nuclear Factor-κB and Adiponectin

Figure 5 | Peroxisome Proliferator-Activated Receptor α Reduces Endothelin-1-Caused Cardiomyocyte Hypertrophy by Inhibiting Nuclear Factor-κB and Adiponectin 