Research Article

Angiopoietin-2 Is an Early Indicator of Acute Pancreatic-Renal Syndrome in Patients with Acute Pancreatitis

Table 2

Laboratory data in the whole group of patients with acute pancreatitis ().

Variable24 hours48 hours72 hoursReference values

Ang-2 [ng/mL]3.18 (2.10–4.64)3.33 (2.06–5.65)3.12 (2.17–5.21)1.73 ± 0.38 (range: 1.17–2.47)
CRP [mg/L]14.00 (2.60–86.70)119.70 (52.00–237.40)104.80 (33.80–227.80)<5.0
WBC [×103/L]11.21 (9.55–15.05)9.80 (6.62–12.87)8.43 (6.17–10.62)4.00–10.00
HCT [%]42.8 (39.1–45.5)39.8 (35.1–42.8)39.5 (35.4–42.2)F: 37.0–47.0/M: 40.0–54.0
PLT [×103/L]234 (188–259)197 (160–230)206 (168–246)150–350
Amylase [U/L]1069 (618–1844)162 (114–316)92 (62–152)62–220
Glucose [mmol/L]7.81 (6.43–10.52)5.39 (4.53–6.20)5.28 (4.76–6.42)3.3–5.6
Urea [mmol/L]6.07 (4.31–7.97)4.36 (3.35–7.33)4.39 (3.35–5.44)2.76–8.07
Creatinine [mol/L]76.0 (65.7–99.1)70.9 (62.4–90.7)70.5 (57.7–89.1)45.0–97.0
Fibrinogen [g/L]2.80 (2.20–3.55)3.87 (3.11–4.98)4.49 (3.52–5.36)1.8–3.5
D-dimer [g/L]1683 (982–3293)2076 (1300–4512)2039 (975–4670)<500
sNGAL [g/L]117.1 (70.8–208.5)170.9 (100.8–237.1)166.7 (102.2–216.6)F: 21.6–276.0/M: 14.4–169.2
uNGAL [g/L]28.5 (15.5–57.0)38.3 (16.5–95.3)41.7 (17.0–65.1)<131.7
uACR [mg/g]43.3 (21.0–79.4)35.8 (20.8–89.5)22.2 (14.2–92.3)<30

Data are presented as median (lower–upper quartile); reference values established in 21 healthy controls; Ang-2: angiopoietin-2; CRP: C-reactive protein; WBC: white blood cells; HCT: hematocrit; PLT: platelets; NGAL: neutrophil gelatinase-associated lipocalin in (s) serum and (u) urine; uACR: urine albumin/creatinine ratio.