Metformin Prevents Fatty Liver and Improves Balance of White/Brown Adipose in an Obesity Mouse Model by Inducing FGF21

<div>Metformin suppressed visceral fat and browning of white adipose tissue (WAT). (a) The epididymal fat and interscapular WAT weight in mice. (b) Visceral fat tissues hematoxylin and eosin staining. (c and d) Relative gene expression associated with (c) WAT and (d) brown adipose tissue (BAT) in visceral fat. 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Mediators of Inflammation

fig4

Figure 4

Figure 4: Metformin Prevents Fatty Liver and Improves Balance of White/Brown Adipose in an Obesity Mouse Model by Inducing FGF21 